Smile lines (also called nasolabial folds) are the creases that run from the sides of the nose to the corners of the mouth. Normally, they appear when you smile, laugh, or move your facial muscles. But if these lines are visible even when your face is at rest, it may be a sign that the skin and bone structure are changing, making the face look older.
Several factors can make smile lines deeper and more noticeable:
Smile lines aren’t just for older people. Younger individuals can also develop them due to factors like frequent smiling and laughing, sleeping on the side or face-down, poor skincare habits, lack of sleep, dehydration, rapid weight loss, or simply genetics and natural facial structure.
One of the most popular treatments for smile lines is the filler injection program. By injecting hyaluronic acid (HA) into the folds, the skin becomes smoother and fuller right away, giving the entire face a fresher, younger appearance.
HA filler program is designed to mimic the body’s natural HA. They are FDA-approved in Thailand and internationally for safety. Filler program helps plump deep folds, restore lost volume, lock in moisture, and improve skin elasticity. Over time, they dissolve naturally and leave no residue.
Filler program can be done from age 18 and above. Even younger clients with visible smile lines can consult a doctor to check if the treatment is suitable.
Hyaluronic acid (HA) filler program has been used for decades to restore facial volume and is widely accepted in dermatology worldwide. It is considered a very safe procedure.
Cases of unsafe filler injection programs usually come from three major issues:
Before any treatment, it’s important to research the clinic carefully. Make sure the injections are performed by a licensed doctor and that only genuine, verifiable products are used. If the clinic cannot guarantee these, it’s safer to choose a certified and trusted provider instead.
The amount depends on the depth and severity of each person’s folds. Doctors adjust to ensure a natural result. On average, 2–4 CCs are typically used.
Filler program gradually settles and shows full results within about 1 month.
On average, results last 8–12 months, as HA naturally breaks down in the body.
The breakdown rate varies based on lifestyle, metabolism, and facial movement, especially since the mouth area moves frequently (talking, chewing, smiling). This often makes HA filler program in this area last slightly shorter than in other zones.
For continuous youthful results, top-ups every 8–12 months are recommended, or whenever lines become noticeable again.
Because genuine HA filler programs are biocompatible with the body, they can be safely repeated under a doctor’s care.
The right treatment depends on each person’s skin condition. Doctors will design a plan tailored to the problem.
For direct smile line correction:
For sagging cheeks (a common cause of deeper smile lines):
At MEGA CLINIC, our doctors recommend three trusted filler program brands for treating deep smile lines:
Among these, Neuramis is the No.1 Korean filler program brand, with the most popular Neuramis Deep (Black Box). Its gel texture is suitable for multiple areas of the face, including smile lines, providing natural, noticeable results at an accessible price—making it one of the best value options today.
Before filler programs, to reduce the chance of noticeable bruising, prepare by:
After getting proper aftercare helps HA settle and last longer. Be sure to:
Other than that, you can continue your daily routine as usual like washing your face, applying skincare, using masks, or being around regular heat such as warm showers, cooking, or eating hot food.
With so many clinics available, it’s important to choose the best for safety, value, and beautiful results. So you won’t be disappointed later. Always consider:
At MEGA CLINIC, safety and quality always come first. Every procedure is performed by experienced doctors using only verifiable, genuine filler programs—ensuring natural, confident results every time.
A: Filler programs are much less painful than most people expect. During the procedure, cold compresses are used, and most filler programs already contain lidocaine (a numbing agent). If needed, numbing cream can also be applied.
Some mild swelling may appear in the first 7–14 days, which is normal before the HA fully settles.
A: It’s common to feel small bumps or firmness right after treatment. Over the next 4 weeks, the HA gradually integrates into the skin, becoming smooth and natural.
A: Filler programs are injected only into the folds to smooth and lift the skin, not to enlarge the cheeks. An experienced doctor will carefully select the type and amount to ensure natural results, leaving your face looking refreshed, not overfilled.
A: Yes. If suitable, your doctor may recommend combining both. Filler program plumps and smooths the deep folds, while Ultraformer III tightens sagging skin. Together, they deliver stronger results: youthful contours, softened folds, firmer skin, and prevention of deeper lines in the future.
If you want fast improvement, a regular HA filler program is often enough. But if you’re looking for longer-lasting results and stronger skin support, the HArmonyCa program may be the better option. A doctor’s consultation is essential to decide the most suitable choice.
MEGA CLINIC has multiple locations covering key areas in Bangkok and nearby provinces:
For more details or to book an appointment, message our admin team via LINE Official: @megaclinic (with @). Click the green “Add LINE” button at the bottom of the screen.