Which treatment is suitable for whom?
In recent years, there have been more choices of skin-focused treatments in the Skin Booster and Collagen Booster categories. Each option has its own strengths in helping the skin look smoother, brighter, more hydrated, and healthier—in different ways.
Two of the most popular options right now are Juvelook (จูวีลุค) vs Rejuran (รีจูรัน). Many people may still be unsure how they differ and which one is best suited for their skin. This article will break down the comparison in a simple, easy-to-understand way, so you can choose what matches your skin goals best.
What is the Juvelook program?
Juvelook (จูวีลุค) is a Collagen Booster treatment designed to rejuvenate the skin from within. Its key ingredient is PDLLA (Poly D,L-Lactic Acid) which stimulates collagen production beneath the skin, helping the skin look firmer, plumper, and smoother. It also contains Hyaluronic Acid (HA) to boost hydration and naturally soften the appearance of fine lines and small skin creases.
What makes Juvelook stand out?
Juvelook isn’t just about improving overall facial skin quality—it’s also effective at treating deeper or stubborn lines that fillers or Botox can’t always fix.
Key features of Juvelook include:
- Reducing fine lines around the eyes, crow’s feet, frown lines, and forehead creases
- Treating stretch marks or small scratch-like scars on the body
- Softening neck lines that cause an aged look
- Stimulating long-term collagen production beneath the skin
- Refining rough skin texture, making it feel firmer and smoother
- Acting as a skin booster to plump the skin and tighten pores across the face
Who is Juvelook best for?
Juvelook is ideal for those seeking gradual but visible improvements in skin quality. As collagen builds over time, the skin becomes noticeably firmer and more supple. It’s especially suitable for people with the following issues:
- Hollow or dark under-eye areas that make the face look tired
- Stretch marks, minor scratch scars, or shallow scarring
- Neck wrinkles that add years to one’s appearance
- Rough, uneven skin with surface-level wrinkles
- Enlarged pores and lack of smoothness in skin texture
Juvelook results from MEGA CLINIC clients
Results from Juvelook as a skin booster: improves skin texture, making it firmer and more refined.
Results from Juvelook for under the eyes: helps reduce fine wrinkles and dullness, making the area look brighter and smoother.
Results from Juvelook on the neck: softens deep neck lines, restoring a more youthful, even-toned appearance.
What is Rejuran?
Rejuran is a type of Skin Booster treatment that deeply repairs and strengthens the skin. Its key ingredient is Polynucleotide (PN) , derived from salmon DNA, which is biologically similar to human DNA. It works to restore damaged skin structures and improve the skin’s overall resilience.
It also stimulates collagen and hyaluronic acid production, leaving the skin hydrated, radiant, and refined with a healthy, Korean-style glow.
What makes Rejuran stand out?
When Rejuran is injected, the Polynucleotides work at the skin’s structural level—not just the surface—to restore vitality and improve texture. The result is plumper, smoother, glass-like skin.
Key features of Rejuran include:
- Tightens pores and smooths shallow acne scars, improving uneven skin texture
- Promotes collagen and new skin cell production, making the skin firmer and smoother
- Boosts skin hydration and glow, delivering a natural glass-skin effect
- Repairs skin from within, not just on the surface
- Strengthening your skin’s natural barrier reducing redness, stinging, and irritation
Who is Rejuran best for?
Rejuran is ideal for people who want to improve overall skin health. Instead of targeting just one area, it works to restore and strengthen the entire face, making the skin more even, smooth, and makeup-friendly. It suits all skin types and is especially helpful for those with:
- Enlarged pores, shallow acne scars, and uneven skin texture
- Dry, dehydrated skin that doesn’t hold makeup well
- Weak, sensitive, easily inflamed skin
- A desire to enhance overall skin quality
- Red acne marks or blemish-prone skin
Rejuran results from MEGA CLINIC clients
Results from Rejuran injectionsshow restored skin structure and improved hydration, creating a plump, radiant, and dewy complexion:
Juvelook vs Rejuran: Side-by-side comparison
Here’s a summary chart provided by the doctor to highlight the key differences between Juvelook and Rejuran:
Read the full article
FAQ: Common questions about Juvelook and Rejuran injections
Q: Is Juvelook safe?
Juvelook is approved by both the Thai FDA and the Korean equivalent. Its key ingredient, PDLLA (Poly D,L-Lactic Acid), is biocompatible, meaning it works naturally with the body to stimulate collagen production. It is fully biodegradable, leaves no residue, and does not form lumps under the skin.
Q: How many types of Rejuran are there? What’s the difference between the red and black box?
At MEGA CLINIC, we offer two types of Rejuran:
- Rejuran Healer (black box) Ideal for overall skin rejuvenation. It helps strengthen the skin barrier, tighten pores, and boost hydration.
- Rejuran HB plus (red box) Contains added hyaluronic acid (HA) for extra hydration and includes an anesthetic (Lidocaine) to reduce stinging during the injection.
Q: Can I get Juvelook and Rejuran injections together?
Yes, they can be used together. However, for skin booster-type injections, it’s recommended to space them at least 4 weeks apart to allow each formula to work effectively without interference.
Q: Can I wear makeup after Juvelook or Rejuran injections?
After a Juvelook injection, avoid wearing makeup for at least 24 hours. You may notice small bumps where the solution was injected; allowing time for them to settle helps prevent inflammation or infection.
The same applies to Rejuran—refrain from makeup for at least one day post-treatment. There may be tiny needle marks on the face, and avoiding cosmetics helps prevent irritation. Once your skin has healed, you can resume your regular makeup routine.
Q: Are Juvelook and Rejuran injected manually or with a device?
For Juvelook, skin booster injections are usually administered using the Hycoox device, which helps evenly distribute the product and stimulates skin renewal. However, for targeted areas like under the eyes, neck, or stretch marks, the doctor will inject manually.
Rejuran is always injected manually using Rejuran’s specific fine needle, which allows the product to reach the deeper skin layers for optimal results. If you prefer using the Hycoox device, let the clinic staff know in advance (additional charges apply).
Want a doctor’s consultation before deciding?
If you’re still unsure whether Juvelook or Rejuran is right for your skin, we recommend consulting with our medical team first. They’ll assess your skin condition, identify areas of concern, and suggest the best treatment based on your needs and goals. This ensures safe, targeted care with clear and satisfying results.
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MEGA CLINIC has multiple locations covering key areas in Bangkok and nearby provinces:
- MEGA CLINIC Siam Square (Bangkok)
BTS Siam, located at the open area near Inter Restaurant Parking available in front of the clinic - MEGA CLINIC Central WestGate (Nonthaburi)
MRT Talad Bang Yai, located on 2nd floor, Central Westgate (Central zone) - MEGA CLINIC Central Ladprao (Bangkok)
BTS Ha Yaek Lat Phrao / MRT Phahon Yothin Located on 9th floor, Central Ladprao (Use Entrance C elevator) - MEGA CLINIC Future Park Rangsit (Pathum Thani)
Located on G floor, Future Rangsit (Robinson zone, next to Watsons) - MEGA CLINIC Pak Nam BTS Srinagarindra (Samut Prakarn)
BTS Srinagarindra, next to Exit 4 staircase Parking available in front of the clinic
Our clinic is easy to reach (view maps) and offers a full range of beauty treatments, including filler programs, Botox programs, skincare, facial lifting programs, anti-aging solutions, and even weight-loss programs. We also provide free consultations with doctors before you decide on any treatment.
For more details or to book an appointment, message our admin team via LINE Official: @megaclinic (with @). Click the green “Add LINE” button at the bottom of the screen.









