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What is the Sculptra program? How much does it cost? What does it help with? Is it truly the ultimate anti-aging skin treatment?

As we enter our 30s, many of us begin to notice signs of skin laxity, loss of firmness, and the early appearance of fine lines. This is because the body’s collagen production gradually declines by approximately 1.5% each year at this stage of life. While natural collagen production slows down, it can be replenished through advanced innovations such as the Sculptra program—a treatment that has been carefully developed and clinically studied to stimulate collagen production in a targeted way.
In this article, our doctor will answer some of the most frequently asked questions about Sculptra: what it is, who it’s suitable for, how much it costs, how it works to stimulate collagen, and key information you should know before deciding on treatment.

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Getting to Know the Sculptra Program: What Is It and How Does It Help Lift and Firm the Skin?

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What is the Sculptra program?

The Sculptra program is a biostimulator treatment designed to stimulate collagen production. It contains Poly-L-Lactic Acid (PLLA), a biocompatible polymer that supports the skin’s natural collagen regeneration process. This helps restore youthful-looking skin, improving firmness and volume from deep within the skin’s structure.
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What is PLLA? Is it safe?

Poly-L-Lactic Acid (PLLA) is an ingredient approved for medical use by both the U.S. Food and Drug Administration (FDA) and Thailand’s Food and Drug Administration (FDA Thailand). Since 2009, PLLA has been widely used in aesthetic medicine to help improve skin elasticity and reduce facial wrinkles, especially in individuals experiencing skin laxity or age-related collagen loss.

What is collagen and why is it important for our skin?

Collagen is an essential protein naturally produced by the body and serves as a key structural component of the skin, muscles, and bones. In the skin, collagen provides strength and elasticity, helping the skin appear smooth, firm, and lifted. When collagen levels decrease, wrinkles become more visible and the skin begins to lose firmness.

At what age does collagen start to decline?

In general, collagen production begins to decline around the age of 25 and continues to decrease each year at an average rate of 1–1.5%. From the age of 30 onward, many people start to notice visible changes such as fine lines, skin laxity, and reduced firmness—largely due to this gradual loss of collagen.

How does the collagen-stimulating process of the Sculptra program work?

Collagen is produced by specialized cells called fibroblasts. As we age, fibroblasts become less active and decrease in number, leading to reduced collagen production and visible skin sagging.
During the Sculptra treatment, PLLA is injected into the deeper layers of the skin, where it signals fibroblasts to activate and increase in number. This stimulates new collagen production over time.
Approximately 2–3 days after injection, some individuals may notice that fine lines appear slightly more visible. This happens because the water and other components of the product are naturally absorbed by the body—a normal part of the process. Once only the PLLA particles remain, collagen regeneration begins more actively.
Over time, the PLLA particles gradually break down, while the newly stimulated collagen continues to build and remain in the skin. This strengthens the skin’s internal structure, resulting in firmer, fuller-looking skin, improved overall skin quality, and a naturally youthful appearance.

What does the Sculptra program help with?

  • Firm and plump up the skin
  • Make skin look younger
  • Reduce wrinkles
  • Tighten the skin
  • Strengthen the skin
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Who is the Sculptra program suitable for?

  • Those with sagging, loose skin who want to lift and firm their skin
  • Those with visible wrinkles, both deep and fine lines
  • Those with a lack of skin elasticity who want firmer, fuller skin
  • Those who want a younger, brighter skin
  • Those with weak skin who want stronger skin
  • Individuals seeking long-term, deep skin rejuvenation.

How is the Sculptra program different from dermal fillers?

Many people wonder how the Sculptra program differs from dermal filler injections , as both treatments are known for making the face look younger. In reality, Sculptra and fillers address different issues and provide different results
  • Sculptra program focuses on improving overall skin quality by stimulating the body’s natural collagen production. This helps strengthen the skin’s structure from within. Because it works by regenerating collagen in the deeper layers of the skin, results are not immediate, but they are long-lasting.
  • Dermal fillers use Hyaluronic Acid (HA) to reshape facial contours and fill in deep lines or hollow areas. The filler material can be molded or adjusted to achieve the desired shape, with visible results appearing immediately after treatment. Results typically last around 8–12 months.
How is Sculptra different from fillers?

How to prepare before receiving the Sculptra injection program

If you are concerned about needle marks or bruising after injections, follow these tips to prevent prolonged recovery
  • Avoid alcohol for at least 24 hours before the injection.
  • Stop taking painkillers, aspirin, and NSAIDs at least 2 weeks before the injection.
  • Avoid certain medications, vitamins, and supplements such as vitamin E, vitamin K, fish oil, and Evening Primrose oil for at least 2 weeks before the injection.
Do not undergo the procedure if you are pregnant or breastfeeding. If you have any medical conditions or are taking medications, consult a doctor before getting the injection.

Post-injection care

The Sculptra program is a treatment that allows you to resume your normal daily activities immediately after injection, with no downtime required. Post-treatment recommendations are as follows:
  • Swelling or redness may occur but will gradually subside.
  • Use the ‘Triple 5’ massage technique: massage for 5 minutes, 5 times a day, for 5 days to help distribute the product evenly and stimulate collagen production.
  • You can wear makeup 24 hours after the injection.
  • Avoid alcohol for 3 days to prevent prolonged bruising.
  • Avoid laser treatments, saunas, and steam rooms for 1 week.
Facial massage after Sculptra injections

Facial massage after the Sculptra injection program

Massaging after Sculptra injections helps the product absorb well and distribute evenly. Use the Triple 5 technique: massage for 5 minutes, 5 times a day, for 5 days.
  • Make a fist and use your thumb to gently massage from the temples to the sides of the hairline
  • Using the same fist, massage from the cheeks to the sides of the face
  • Use the palm of your hand to massage from the side of your face up to the cheekbones.
  • Make a fist and use your thumb to massage from the chin to the jawline

When will results from the Sculptra program be visible, and how long do they last?

Sculptra works by rejuvenating the deep structure of the skin, making it gradually firmer and tighter by the 4th week, with significant reduction in sagging by the 3rd month.
3 sessions of Sculptra injections, spaced 1 month apart, allow the skin to fully produce collagen, with results lasting up to 2 years. A single session will provide results lasting about 6-7 months.

Real customer reviews

Where is a good place to get the Sculptra program? How to choose a certified clinic

Sculptra program is a treatment that requires medical expertise and is relatively high in cost, so careful consideration is essential before making a decision. Here are some recommended guidelines to help you choose a certified clinic, ensuring professional care and results that meet your expectations.
  1. The clinic is properly licensed All medical clinics must have an official operating license issued by the Ministry of Public Health, which should be clearly displayed at the clinic.
  2. The injector is a licensed medical doctor Many aesthetic procedures—especially the Sculptra program—require a high level of precision and expertise. Treatment should be performed by an experienced physician. You may request the doctor’s full name or medical license number (MD license) from the clinic and verify it on the Medical Council of Thailand website: https://checkmd.tmc.or.th
  3. Authentic Sculptra products can be verified Certified clinics must source Sculptra directly from Galderma, the official manufacturer. Patients can request to inspect the product packaging before opening to confirm authenticity.
  4. Clear and thorough consultation A reputable clinic should clearly explain how the Sculptra program differs from other treatments, including its benefits, limitations, expected timeline for results, and realistic outcomes.
  5. Real reviews and post-treatment follow-up Look for genuine patient reviews, including before-and-after photos, to support your decision. After treatment, the clinic should provide follow-up appointments to assess results, satisfaction, and address any concerns.
Now that you know how to identify a trustworthy clinic, many people may also wonder how to verify authentic Sculptra products. Let’s take a closer look at how to check the packaging in detail in the next section.

How to identify authentic Sculptra products

Authentic Sculptra products can be identified by the following five key features:
  • The box has a hologram sticker printed with the word GALDERMA.
  • There is an embossed “S” watermark on the front of the box that can be felt by touch.
  • The box displays a Thai FDA registration number along with an accompanying Thai-language information leaflet.
  • A QR code is located on the side of the box and can be scanned via the eZTracker application to verify authenticity.
  • The vial is vacuum-sealed and contains no liquid inside.

How much does the Sculptra program cost?

Sculptra Program (10 cc per vial) priced at 22,999 THB
  • Purchase 2 vials: 3,000 THB
  • Purchase 3 vials: 9,000 THB
  • Purchase 4 vials: 12,000 THB

FAQ – Frequently Asked Questions

Q: Besides the Sculptra program, what other biostimulator treatments are available?

A: At MEGA CLINIC, there are additional biostimulator treatments available, including the Juvelook program and the HArmonyCa program, allowing patients to choose the option that best suits their needs, concerns, and readiness.

Juvelook

  • Ingredients: Hyaluronic Acid (HA) และ Poly-D,L-lactic acid (PDLLA)
  • Suitable areas: Under-eye area, nasolabial folds, forehead, and neck
  • Benefits: Helps reduce fine lines under the eyes, fill in deeper lines, stimulate collagen production, and support long-term skin elasticity
  • Ideal for: Individuals aged 25 and above

Program HArmonyCa

  • Ingredients: HA และ Calcium Hydroxyapatite (CaHA) ยกกระชับผิวหน้าและกระตุ้นการสร้างคอลลาเจนใหม่
  • Suitable areas: Temples, cheeks, nasolabial folds, marionette lines, jawline, and chin
  • Benefits: Helps add firmness and lift, reduce skin sagging, and stimulate long-term collagen production
  • Ideal for: Individuals aged 35–40 and above with skin laxity concerns

Q: Is the Sculptra injection program effective?

Sculptra addresses skin issues by stimulating the body’s collagen production directly, with ingredients derived from natural sources that break down safely. It’s a worthwhile treatment with clear, long-lasting results, perfect for those wanting to rejuvenate their skin.

Q: How many sessions are required for the Sculptra program?

A: Doctors usually recommend getting Sculptra injections 2-3 times at first, with about 1 month between each session. This helps boost collagen production and makes the skin firmer.

Q: Is the Sculptra injection painful?

A: At MEGA CLINIC, we apply numbing cream before giving Sculptra injections, so it hurts very little. However, pain sensitivity can differ for each person depending on how sensitive their skin is. If you are mentally and physically ready, the injection process will feel much more comfortable and relaxing than you might expect.

Q: Is there significant swelling after the Sculptra injection?

A: After the injection, there may be some swelling at the injection site, which is normal. The swelling usually goes down within 2-3 days, depending on your skin type. For some people, the swelling is so minimal it’s barely noticeable.

Do the results of the Sculptra program compare to Ultraformer III?

A: While both treatments help lift and firm the skin, Sculptra and Ultraformer III work differently. Ultraformer III focuses on lifting and reducing sagging skin, while Sculptra improves skin firmness and overall skin quality, making you look younger.

Q: How many cc are there in one vial of Sculptra?

A: One bottle of Sculptra contains 10 CCs.

Q: Can Sculptra results last up to 2 years?

A: Sculptra results can last up to 2 years if you get injections once a month for 3 months. However, if you only get one session, the results will last about 6-7 months.
MEGA CLINIC has multiple locations covering key areas in Bangkok and nearby provinces:
  • MEGA CLINIC Siam Square (Bangkok)
    BTS Siam, located at the open area near Inter Restaurant Parking available in front of the clinic
  • MEGA CLINIC Central WestGate (Nonthaburi)
    MRT Talad Bang Yai, located on 2nd floor, Central Westgate (Central zone)
  • MEGA CLINIC Central Ladprao (Bangkok)
    BTS Ha Yaek Lat Phrao / MRT Phahon Yothin Located on 9th floor, Central Ladprao (Use Entrance C elevator)
  • MEGA CLINIC Future Park Rangsit (Pathum Thani)
    Located on G floor, Future Rangsit (Robinson zone, next to Watsons)
  • MEGA CLINIC Pak Nam BTS Srinagarindra (Samut Prakarn)
    BTS Srinagarindra, next to Exit 4 staircase Parking available in front of the clinic
Our clinic is easy to reach (view maps) and offers a full range of beauty treatments, including filler programs, Botox programs, skincare, facial lifting programs, anti-aging solutions, and even weight-loss programs. We also provide free consultations with doctors before you decide on any treatment.
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For more details or to book an appointment, message our admin team via LINE Official: @megaclinic (with @). Click the green “Add LINE” button at the bottom of the screen.
Reference: Sculptra: What It Is, Where It’s Injected, Results & Risks จาก my.clevelandclinic.org