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What is HarmonyCa? Who Is It For? A Deep Dive into the Hybrid Face-Lifting Filler for Volume, Lift & Skin Rejuvenation in One Treatment

As we age, our skin starts to lose its firmness. On top of that, problems like wrinkles, fine lines, and sagging skin begin to appear. This happens because the skin's support structure weakens, and collagen levels decrease over time. But don’t worry—there’s a solution! Introducing HArmonyCa, a treatment that effectively addresses these concerns in just one session.
In this article, I’ll explain everything about HArmonyCa, a treatment that lifts the skin and boosts collagen naturally for long-lasting results. We’ll go in-depth about what HArmonyCa does, its key benefits, who it’s suitable for, and even answer the common question: How much does HArmonyCa cost? By the end, you’ll have all the information you need to decide if this treatment is right for you.

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What is HArmonyCa?

HarmonyCa is a treatment that helps restore facial volume and instantly lift the skin after injection, while stimulating fibroblasts to naturally produce collagen. As a result, the skin appears more elastic, firm, and wrinkles are reduced. It works together with HA (Hyaluronic Acid), which helps fill the skin and maintain results for 6–12 months, and CaHA (Calcium Hydroxyapatite), which stimulates collagen production within 1–3 months. The newly generated collagen can last up to 18 months. However, results depend on each individual’s skin condition. In the next section, we will take a closer look at these two key components.
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How does HarmonyCa work? Understanding the Dual Effect mechanism for immediate and long-lasting results

Now that we know what HarmonyCa is made of, let’s take a look at how both HA and CaHA, when combined in a single syringe, can benefit our skin and why it is called a Dual Effect treatment.

What does Hyaluronic Acid in HarmonyCa help with?

Hyaluronic Acid (HA) is one of the main components of HarmonyCa, responsible for effectively filling and lifting the skin. It uses a cross-linked form of HA, which is highly stable, helping the results last longer and look more natural. Once injected, it helps reshape the face and address various concerns, such as:
  • Fill wrinkles and reshape the face
  • Instant skin lifting after injection
  • Reduce the appearance of deep lines, making them look smoother
  • Increase hydration for plump and refreshed-looking skin
Those who are familiar with dermal fillers may already know what Hyaluronic Acid is and what its properties are. But for those who are not yet familiar, the following article will explain this component in detail.

Calcium Hydroxyapatite (CaHA) stimulates collagen in the skin, helping to rejuvenate from within.

Calcium Hydroxyapatite (CaHA) is especially important for those who are getting older and are regularly exposed to UV radiation from sunlight. These factors reduce the number of fibroblasts, the key cells responsible for collagen production, leading to sagging skin, loss of firmness, and the appearance of wrinkles. CaHA plays an important role in:
  • Stimulating the production of Collagen Type I, the primary collagen that helps keep the skin firm
  • Rebuilding the skin’s structure from within
When working together with HA, which helps cells retain moisture, the skin is provided with an ideal environment for collagen production, resulting in firmer, tighter, and more youthful-looking skin.

What does HArmonyCa do?

  • Helps restore volume and lift the skin’s appearance
  • Helps naturally stimulate collagen production
  • Improves skin firmness and prevents sagging
  • Enhances skin elasticity
  • Reduces the appearance of fine lines
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Who is HArmonyCa good for?

  • Those who develop smile lines or sagging along the cheeks when smiling
  • Individuals with deep nasolabial folds or marionette lines
  • People experiencing skin laxity or sagging
  • Those with drooping cheek pouches that make the face look tired
  • Individuals with loose skin and lack of facial definition
  • People who want a facelift effect without surgery

- Who should avoid this treatment?

  • Individuals with a history of allergy to HA injections
  • Women who are pregnant or breastfeeding
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Which areas can be injected?

Before the injection, the doctor will assess the face and skin structure to determine the appropriate injection points, which may include the following areas:
  • Temple
  • Mid-cheeks
  • Nasolabial folds (Smile lines)
  • Marionette lines
  • Face frame
  • Chin wrinkles:

How many syringes are needed?

The doctor will first assess the suitability of your facial structure before deciding how many syringes are needed. In general, about 1–2 syringes per side are typically used.
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Steps for Getting HarmonyCa at MEGA CLINIC

The doctor thoroughly evaluates the skin concerns

Before starting the procedure, the doctor will assess the skin condition, facial structure, and individual concerns in detail, in order to create the most suitable injection plan for each person — including both the injection sites and the amount of syringes required.

Product verification

Every box of HarmonyCa can be verified by checking the lot number and FDA approval status to ensure it is an authentic product that is safe and meets quality standards.

Begin injecting HarmonyCa according to the treatment plan assessed by the doctor

The doctor will inject into the targeted skin layers that need correction, such as the nasolabial folds, cheeks, temples, or jawline.

Results

  • The face is lifted instantly, giving a sharper contour, while hollow cheeks appear fuller.
  • The skin looks firmer and feels tighter to the touch.
  • Deep chin lines become smoother, and the cheeks are lifted, reducing folds around the mouth.
  • Marionette lines and smile wrinkles are noticeably diminished.
  • The jawline becomes more defined, with the lower face appearing sharper and smoothly connected to the side contours.
  • Results may vary for each individual, depending on skin structure and the degree of facial sagging.

HArmonyCa Before & After

In general, HarmonyCa is suitable for individuals aged 30 and above, especially those in the 50–60 age group. The results can be seen immediately after the injection.
In the case of individuals in their 20s to 30s, they can also receive the treatment, with visible results showing an immediate lifting effect on the face.

How many days does it take to see results with HarmonyCa?

After the injection, you will notice an immediate lifting effect on the face. The skin will begin to feel firmer, fine lines will fade, and the body will gradually start producing new collagen over the course of 1–3 months.

How long does it last?

The results of HArmonyCa can last up to 18 months or 1.5 years.

Things to do before getting HArmonyCa

  • Stop using skincare products that contain Alpha Hydroxy Acid (AHA) and Retinol for 3 days before treatment.
  • Avoid taking NSAIDs (anti-inflammatory drugs) and supplements like Vitamin E, Vitamin K, and fish oil for 1 week before treatment.

Possible Side Effects After Getting HArmonyCa

  • After the injection, mild swelling or itching may occur at the injection site. These symptoms can be relieved by applying a cold compress and will gradually improve within a week.
  • Injection marks and bruises will fade within 7-14 days.

How to care for your skin after a Hycoox injection

  • Avoid facial massages for 1 week. 
  • Avoid activities with high heat, such as saunas and steam rooms, for 1 week.
  • If concerned about bruising, avoid alcohol and smoking for 2 weeks.
  • Since HA works well with water, drinking 7-8 glasses of water per day will help maximize the results.

How is it different from other treatments?

HArmonyCa provides a dual effect by adding volume and lifting the skin instantly while also stimulating long-term collagen production. This makes the results look natural and last longer. It combines the benefits of both Sculptra and Radiesse but stands out in its ability to tighten, firm, and improve skin elasticity while reducing sagging and rejuvenating the skin from within.

I have summarized the comparison table clearly as follows:

เปรัยบเทียบ ฮาโมนิก้า Sculptra และ Radiesse
Both HArmonyCa, Sculptra, and Radiesse can stimulate collagen production. However, there are differences. Sculptra helps improve skin quality, making it firmer and fuller, giving a more youthful look. Radiesse also stimulates collagen and tightens the skin, but it requires at least 3 sessions to see noticeable results.
HArmonyCa is the all-in-one choice because it provides a dual effect—it fills and lifts the skin immediately while also stimulating long-term collagen production. This makes the skin firmer, naturally plump, and gives longer-lasting results.

How is HarmonyCa different from regular fillers, and why is it more expensive?

Since HarmonyCa offers more benefits than just filling deep lines or reshaping the face with HA, like regular fillers do, it also contains CaHA that stimulates collagen production at the same time. This means it not only fills and lifts the skin but also promotes long-term collagen regeneration. The results can last up to 18 months. Because HarmonyCa has additional components and provides longer-lasting effects, its price is higher—but it delivers greater value in the long run.
For those seeking an alternative that offers similar results, combining Ultraformer III with targeted filler injections can be an interesting option. However, the collagen stimulation process works differently, as follows:
  • Ultraformer III uses ultrasound energy to stimulate collagen production beneath the skin.
  • HarmonyCa works directly on fibroblasts to stimulate the body’s natural collagen production.
Ultimately, deciding which treatment is right for you depends on the desired duration of results and overall value. If you are still uncertain, you can consult with a doctor at MEGA CLINIC to receive personalized advice and choose the treatment most suitable for you.
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Is HArmonyCa safe? Where should you get it done?

To ensure safety, choose a certified clinic with these standards:
  • Approved by the Ministry of Public Health.
  • Performed by a qualified and experienced doctor.
  • Uses authentic HArmonyCa from Allergan.
  • Provides aftercare services and doctor consultation.

How much does it cost?

The normal price for HArmonyCa is 34,999 THB per syringe.
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Summary:

HarmonyCa is a hybrid filler that combines the power of Hyaluronic Acid (HA) and Calcium Hydroxyapatite (CaHA) in a single syringe. It helps restore skin volume and lift facial contours from the very first treatment, while continuously stimulating collagen production for up to 18 months. It is ideal for those who want to rejuvenate their face naturally.

Q&A: Everything You Want to Know

Q: How often can I get HArmonyCa?

A: You can repeat the injection every 6 months.

Q: If I’ve already had thread lifting, can I still get injections?

A: Thread lifting is performed in the same skin layer as HArmonyCa injections. If you’ve already had thread lifting, doctors recommend waiting 6–12 months for the threads to dissolve before getting the injection.

Q: Do I need any recovery time after the injection?

A: There’s no real downtime after the injection — you can return to your daily activities right away. Some mild swelling or bruising may occur, but it usually resolves within a few days.

Q: Can I have an allergic reaction to HArmonyCa?

A: No known allergies have been reported, as HA and CaHA are naturally found in the body and dissolve over time within 6–12 months.

Q: What treatments can be done together with the injection?

A: It can be combined with other treatments. Even though it contains HA like fillers, it can still be done together with fillers since they are injected into different skin layers.

Q: Besides HArmonyCa, what other biostimulator treatments are available?

A: There are 2 other procedures — Juvelook and Sculptra Both stimulate collagen production, but each has different properties and suitability. The article below explains the differences in detail.
Visit MEGA CLINIC at any of our 5 branches for a detailed consultation with our doctors—free of charge:
  • MEGA CLINIC, aesthetic clinic, Bangkok
  • MEGA CLINIC, aesthetic clinic, Nonthaburi
  • MEGA CLINIC, aesthetic clinic, Lad Prao
  • MEGA CLINIC, aesthetic clinic, Rangsit, Pathum Thani
  • MEGA CLINIC, aesthetic clinic, Pak Nam (Srinagarindra)
Get a basic consultation with our staff via LINE Official: @megaclinic (don’t forget the @) or simply click the green button below to add us on LINE.
Reference:
What are Calcium Hydroxylapatite Injections? form plasticsurgery.org